5TZ2
Crystal structure of human CD47 ECD bound to Fab of C47B222
Summary for 5TZ2
Entry DOI | 10.2210/pdb5tz2/pdb |
Related | 5TZT 5TZU |
Descriptor | C47B222 Fab Heavy Chain, C47B222 Fab Light Chain, Leukocyte surface antigen CD47, ... (7 entities in total) |
Functional Keywords | antigen-fab complex, immunoglobulin, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 64418.74 |
Authors | Cardoso, R.M.F. (deposition date: 2016-11-21, release date: 2017-03-15, Last modification date: 2023-10-04) |
Primary citation | Pietsch, E.C.,Dong, J.,Cardoso, R.,Zhang, X.,Chin, D.,Hawkins, R.,Dinh, T.,Zhou, M.,Strake, B.,Feng, P.H.,Rocca, M.,Santos, C.D.,Shan, X.,Danet-Desnoyers, G.,Shi, F.,Kaiser, E.,Millar, H.J.,Fenton, S.,Swanson, R.,Nemeth, J.A.,Attar, R.M. Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies. Blood Cancer J, 7:e536-e536, 2017 Cited by PubMed: 28234345DOI: 10.1038/bcj.2017.7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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