5TZ2
Crystal structure of human CD47 ECD bound to Fab of C47B222
Functional Information from GO Data
Chain | GOid | namespace | contents |
C | 0005886 | cellular_component | plasma membrane |
C | 0022409 | biological_process | positive regulation of cell-cell adhesion |
C | 0050729 | biological_process | positive regulation of inflammatory response |
C | 0050766 | biological_process | positive regulation of phagocytosis |
C | 0070053 | molecular_function | thrombospondin receptor activity |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
Chain | Residue | Details |
L | TYR192-HIS198 | |
H | TYR201-HIS207 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 122 |
Details | TOPO_DOM: Extracellular => ECO:0000255 |
Chain | Residue | Details |
C | GLN1-GLU123 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:18657508 |
Chain | Residue | Details |
C | GLN1 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P97829 |
Chain | Residue | Details |
C | SER71 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508 |
Chain | Residue | Details |
C | ASN5 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
Chain | Residue | Details |
C | ASN16 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19349973 |
Chain | Residue | Details |
C | ASN32 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 |
Chain | Residue | Details |
C | ASN55 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218 |
Chain | Residue | Details |
C | ASN93 |