5TZU
Crystal structure of human CD47 ECD bound to Fab of B6H12.2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0022409 | biological_process | positive regulation of cell-cell adhesion |
| C | 0050729 | biological_process | positive regulation of inflammatory response |
| C | 0050766 | biological_process | positive regulation of phagocytosis |
| C | 0070053 | molecular_function | thrombospondin receptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR199-HIS205 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| C | GLN1-GLU123 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:18657508 |
| Chain | Residue | Details |
| C | GLN1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P97829 |
| Chain | Residue | Details |
| C | SER71 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508 |
| Chain | Residue | Details |
| C | ASN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| C | ASN16 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| C | ASN32 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| C | ASN55 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18657508, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| C | ASN93 |
