5MEN
Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor
Summary for 5MEN
Entry DOI | 10.2210/pdb5men/pdb |
Related | 4MNQ 5MEO 5MEP 5MEQ 5MER |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ILE-LEU-ALA-LYS-PHE-LEU-HIS-TRP-LEU, ... (9 entities in total) |
Functional Keywords | immuno, hla-a02, 1e6-tcr, cross-reactivity, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 5 |
Total formula weight | 94971.18 |
Authors | Rizkallah, P.J.,Lloyd, A.,Crowther, M.,Cole, D.K.,Sewell, A.K. (deposition date: 2016-11-16, release date: 2016-12-07, Last modification date: 2024-01-17) |
Primary citation | Cole, D.K.,van den Berg, H.A.,Lloyd, A.,Crowther, M.D.,Beck, K.,Ekeruche-Makinde, J.,Miles, J.J.,Bulek, A.M.,Dolton, G.,Schauenburg, A.J.,Wall, A.,Fuller, A.,Clement, M.,Laugel, B.,Rizkallah, P.J.,Wooldridge, L.,Sewell, A.K. Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292:802-813, 2017 Cited by PubMed: 27903649DOI: 10.1074/jbc.M116.741603 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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