5K16

Crystal structure of free Ubiquitin-specific protease 12

Summary for 5K16

Entry DOI	10.2210/pdb5k16/pdb
Related	5K19 5K1A 5K1B 5K1C
Descriptor	Ubiquitin carboxyl-terminal hydrolase 12, ZINC ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	deubiquitination, deubiquitnating enzyme, dub, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	82828.37
Authors	Li, H.,D'Andrea, A.D.,Zheng, N. (deposition date: 2016-05-17, release date: 2016-07-20, Last modification date: 2023-09-27)
Primary citation	Li, H.,Lim, K.S.,Kim, H.,Hinds, T.R.,Jo, U.,Mao, H.,Weller, C.E.,Sun, J.,Chatterjee, C.,D'Andrea, A.D.,Zheng, N. Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63:249-260, 2016 Cited by PubMed: 27373336 DOI: 10.1016/j.molcel.2016.05.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.599 Å)

Structure validation