5I42
Structure of HIV-1 Reverse Transcriptase in complex with a DNA aptamer, AZTTP, and CA(2+) ion
Summary for 5I42
Entry DOI | 10.2210/pdb5i42/pdb |
Related | 5D3G 5HP1 5HRO 5I3U |
Descriptor | HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, DNA (38-MER), ... (5 entities in total) |
Functional Keywords | rt, dna aptamer, azttp, polymerase, p site complex, 2-o-methylcytidine, transferase-dna complex, transferase/dna |
Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) More |
Total number of polymer chains | 6 |
Total formula weight | 256199.06 |
Authors | Das, K.,Arnold, E. (deposition date: 2016-02-11, release date: 2016-06-01, Last modification date: 2023-09-27) |
Primary citation | Das, K.,Balzarini, J.,Miller, M.T.,Maguire, A.R.,DeStefano, J.J.,Arnold, E. Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11:2158-2164, 2016 Cited by PubMed: 27192549DOI: 10.1021/acschembio.6b00187 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
Download full validation report