5FFO
Integrin alpha V beta 6 in complex with pro-TGF-beta
Summary for 5FFO
Entry DOI | 10.2210/pdb5ffo/pdb |
Related | 5FFG |
Descriptor | Integrin alpha-V, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (14 entities in total) |
Functional Keywords | integrin, tgf-beta, cell adhesion |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 368616.22 |
Authors | Dong, X.,Zhao, B.,Springer, T.A. (deposition date: 2015-12-18, release date: 2017-01-25, Last modification date: 2020-07-29) |
Primary citation | Dong, X.,Zhao, B.,Iacob, R.E.,Zhu, J.,Koksal, A.C.,Lu, C.,Engen, J.R.,Springer, T.A. Force interacts with macromolecular structure in activation of TGF-beta. Nature, 542:55-59, 2017 Cited by PubMed: 28117447DOI: 10.1038/nature21035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.49 Å) |
Structure validation
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