5UK5
Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)
Summary for 5UK5
Entry DOI | 10.2210/pdb5uk5/pdb |
Related | 2VJ3 4CC0 4D0E 4XL1 4XLW |
Descriptor | Neurogenic locus notch homolog protein 1, Protein jagged-1, alpha-D-xylopyranose-(1-3)-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | notch, jagged, delta, glycoprotein, signaling protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 59432.96 |
Authors | Garcia, K.C.,Luca, V.C. (deposition date: 2017-01-19, release date: 2017-03-08, Last modification date: 2023-10-04) |
Primary citation | Luca, V.C.,Kim, B.C.,Ge, C.,Kakuda, S.,Wu, D.,Roein-Peikar, M.,Haltiwanger, R.S.,Zhu, C.,Ha, T.,Garcia, K.C. Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity. Science, 355:1320-1324, 2017 Cited by PubMed: 28254785DOI: 10.1126/science.aaf9739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.506 Å) |
Structure validation
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