4ZPH
Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine
Summary for 4ZPH
Entry DOI | 10.2210/pdb4zph/pdb |
Related | 4ZP4 4ZPK 4ZPR |
Descriptor | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN, ... (4 entities in total) |
Functional Keywords | hif-2a, arnt, bhlh-pas, proflavine, protein transport-transcription complex, protein transport/transcription |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus: P53762 P97481 |
Total number of polymer chains | 4 |
Total formula weight | 169485.94 |
Authors | Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. (deposition date: 2015-05-07, release date: 2015-08-12, Last modification date: 2023-09-27) |
Primary citation | Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. Structural integration in hypoxia-inducible factors. Nature, 524:303-308, 2015 Cited by PubMed: 26245371DOI: 10.1038/nature14883 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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