4RPQ
Human Aldose Reductase complexed with a ligand with an IDD structure at 1.20 A (1)
Summary for 4RPQ
Entry DOI | 10.2210/pdb4rpq/pdb |
Related | 1US0 4PUU 4PUW 4Q7B 4QBX 4QR6 |
Descriptor | Aldose reductase, ({3-[(3-nitrobenzyl)carbamoyl]biphenyl-4-yl}oxy)acetic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | tim barrel, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15121 |
Total number of polymer chains | 1 |
Total formula weight | 36916.94 |
Authors | Rechlin, C.,Heine, A.,Klebe, G. (deposition date: 2014-10-31, release date: 2015-11-18, Last modification date: 2023-09-20) |
Primary citation | Rechlin, C.,Scheer, F.,Heine, A.,Diederich, W.,Klebe, G. Aldose Reductase: IDD ligands under investigation To be Published, |
Experimental method |
Structure validation
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