4RPQ
Human Aldose Reductase complexed with a ligand with an IDD structure at 1.20 A (1)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aldose reductase | polymer | 315 | 35767.1 | 1 | UniProt (P15121) Pfam (PF00248) In PDB | Homo sapiens (human) | AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1 |
2 | A | ({3-[(3-nitrobenzyl)carbamoyl]biphenyl-4-yl}oxy)acetic acid | non-polymer | 406.4 | 1 | Chemie (3UH) | |||
3 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
4 | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P15121)
PDB | External Database | Details |
---|---|---|
Ile 4 | Leu 5 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35767.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1149.8 | |
All* | Total formula weight | 36916.9 |