4KFM

Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with the beta-gamma G protein subunits

4KFM の概要

• エントリーDOI: 10.2210/pdb4kfm/pdb
• 関連するPDBエントリー: 3SYA 3SYC 3SYO 3SYP 3SYQ
• 分子名称: G protein-activated inward rectifier potassium channel 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: metal transport, ion channel, potassium channel, inward rectification, sodium binding, pip2 binding, g protein binding
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein (By similarity): Q8C4T8; Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P59768
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 85672.47

構造登録者

Whorton, M.R.,MacKinnon, R. (登録日: 2013-04-27, 公開日: 2013-06-12, 最終更新日: 2013-09-11)

• 主引用文献: Whorton, M.R.,MacKinnon, R.; X-ray structure of the mammalian GIRK2-beta gamma G-protein complex.; Nature, 498:190-197, 2013; PubMed: 23739333; DOI: 10.1038/nature12241

実験手法

X-RAY DIFFRACTION (3.45 Å)