4FX3
Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor
Summary for 4FX3
Entry DOI | 10.2210/pdb4fx3/pdb |
Related | 4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKV 4FKW |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, (3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxylic acid, ... (5 entities in total) |
Functional Keywords | complex (transferase-cyclin), transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 Nucleus : P20248 |
Total number of polymer chains | 4 |
Total formula weight | 128385.01 |
Authors | Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-07-02, release date: 2013-05-15, Last modification date: 2023-09-13) |
Primary citation | Kang, Y.N.,Stuckey, J.A. Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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