4FX3

Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor

Summary for 4FX3

• Entry DOI: 10.2210/pdb4fx3/pdb
• Related: 4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKV 4FKW
• Descriptor: Cyclin-dependent kinase 2, Cyclin-A2, (3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxylic acid, ... (5 entities in total)
• Functional Keywords: complex (transferase-cyclin), transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941; Nucleus : P20248
• Total number of polymer chains: 4
• Total formula weight: 128385.01

Authors

Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-07-02, release date: 2013-05-15, Last modification date: 2023-09-13)

• Primary citation: Kang, Y.N.,Stuckey, J.A.; Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)