4FKS
Crystal structure of the cdk2 in complex with oxindole inhibitor
Summary for 4FKS
| Entry DOI | 10.2210/pdb4fks/pdb |
| Related | 4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKT 4FKU 4FKV 4FKW |
| Descriptor | Cyclin-dependent kinase 2, N-[(4-{[(Z)-(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}phenyl)sulfonyl]acetamide (3 entities in total) |
| Functional Keywords | alpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytoskeleton, centrosome: P24941 |
| Total number of polymer chains | 1 |
| Total formula weight | 34416.99 |
| Authors | Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-06-13, release date: 2013-05-08, Last modification date: 2024-11-27) |
| Primary citation | Kang, Y.N.,Stuckey, J.A. Crystal structure of the cdk2 in complex with oxindole inhibitor To be Published, |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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