4FKS
Crystal structure of the cdk2 in complex with oxindole inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Cyclin-dependent kinase 2 | polymer | 299 | 34002.5 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
2 | B (A) | N-[(4-{[(Z)-(7-oxo-6,7-dihydro-8H-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}phenyl)sulfonyl]acetamide | non-polymer | 414.5 | 1 | Chemie (46K) | |||
3 | C (A) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDB | External Database | Details |
---|---|---|
Ace 0 | - | ACETYLATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34002.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 414.5 | |
All* | Total formula weight | 34417.0 |