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4EK8

Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor

Summary for 4EK8
Entry DOI10.2210/pdb4ek8/pdb
Related4EK3 4EK4 4EK5 4EK6
DescriptorCyclin-dependent kinase 2, 4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine (3 entities in total)
Functional Keywordsalpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, centrosome: P24941
Total number of polymer chains1
Total formula weight34329.89
Authors
Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-04-09, release date: 2013-05-01, Last modification date: 2024-11-06)
Primary citationKang, Y.N.,Stuckey, J.A.
Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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