4EK6

Crystal structure of the cdk2 in complex with aminopyrazole inhibitor

Summary for 4EK6

• Entry DOI: 10.2210/pdb4ek6/pdb
• Related: 4EK3 4EK4 4EK5
• Descriptor: Cyclin-dependent kinase 2, N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-[4-(thiophen-2-yl)phenyl]acetamide (3 entities in total)
• Functional Keywords: alpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941
• Total number of polymer chains: 1
• Total formula weight: 34325.94

Authors

Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-04-09, release date: 2013-05-01, Last modification date: 2024-11-20)

• Primary citation: Kang, Y.N.,Stuckey, J.A.; Crystal structure of the cdk2 in complex with aminopyrazole inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.52 Å)