4FKV

Crystal structure of the cdk2 in complex with oxindole inhibitor

Summary for 4FKV

Related4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKW
DescriptorCyclin-dependent kinase 2, (3Z)-N-[2-(1H-imidazol-4-yl)ethyl]-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxamide, GLYCEROL, ... (4 entities in total)
Functional Keywordsalpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, centrosome P24941
Total number of polymer chains1
Total molecular weight34548.1
Authors
Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-06-13, release date: 2013-05-08, Last modification date: 2013-05-22)
Primary citation
Kang, Y.N.,Stuckey, J.A.
Crystal structure of the cdk2 in complex with oxindole inhibitor
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20920.7%0.4%10.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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