4FX3

Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor

4FX3 の概要

• エントリーDOI: 10.2210/pdb4fx3/pdb
• 関連するPDBエントリー: 4EK3 4EK4 4EK5 4EK6 4EK8 4FKG 4FKI 4FKJ 4FKL 4FKO 4FKP 4FKQ 4FKR 4FKS 4FKT 4FKU 4FKV 4FKW
• 分子名称: Cyclin-dependent kinase 2, Cyclin-A2, (3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxylic acid, ... (5 entities in total)
• 機能のキーワード: complex (transferase-cyclin), transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941; Nucleus : P20248
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 128385.01

構造登録者

Kang, Y.N.,Stuckey, J.A. (登録日: 2012-07-02, 公開日: 2013-05-15, 最終更新日: 2023-09-13)

• 主引用文献: Kang, Y.N.,Stuckey, J.A.; Crystal Structure of the CDK2/Cyclin A complex with oxindole inhibitor; To be Published,

実験手法

X-RAY DIFFRACTION (2.75 Å)