4FQV
Crystal structure of broadly neutralizing antibody CR9114 bound to H7 influenza hemagglutinin
Summary for 4FQV
Entry DOI | 10.2210/pdb4fqv/pdb |
Related | 4FNK 4FQH 4FQI 4FQJ 4FQK 4FQL 4FQM 4FQY |
Descriptor | Hemagglutinin HA1, Hemagglutinin HA2, Antibody CR9114 heavy chain, ... (4 entities in total) |
Functional Keywords | viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Cellular location | Host apical cell membrane ; Single-pass type I membrane protein : Q6VMK1 Q6VMK1 |
Total number of polymer chains | 12 |
Total formula weight | 307968.69 |
Authors | Ekiert, D.C.,Dreyfus, C.,Wilson, I.A. (deposition date: 2012-06-25, release date: 2012-08-22, Last modification date: 2018-01-31) |
Primary citation | Dreyfus, C.,Laursen, N.S.,Kwaks, T.,Zuijdgeest, D.,Khayat, R.,Ekiert, D.C.,Lee, J.H.,Metlagel, Z.,Bujny, M.V.,Jongeneelen, M.,van der Vlugt, R.,Lamrani, M.,Korse, H.J.,Geelen, E.,Sahin, O.,Sieuwerts, M.,Brakenhoff, J.P.,Vogels, R.,Li, O.T.,Poon, L.L.,Peiris, M.,Koudstaal, W.,Ward, A.B.,Wilson, I.A.,Goudsmit, J.,Friesen, R.H. Highly conserved protective epitopes on influenza B viruses. Science, 337:1343-1348, 2012 Cited by PubMed: 22878502DOI: 10.1126/science.1222908 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (5.75 Å) |
Structure validation
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