4DF8

Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with aminopentinyl-7-deaza-2-dATP

Summary for 4DF8

• Entry DOI: 10.2210/pdb4df8/pdb
• Related: 3KTQ 3LWL 3LWM 3M8S 3OJS 3OJU
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (9 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 3
• Total formula weight: 70641.04

Authors

Bergen, K.,Steck, A.,Struett, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A. (deposition date: 2012-01-23, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Bergen, K.,Steck, A.L.,Strutt, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A.; Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.; J.Am.Chem.Soc., 134:11840-11843, 2012; PubMed: 22475415; DOI: 10.1021/ja3017889

Experimental method

X-RAY DIFFRACTION (2 Å)