4DF8
Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with aminopentinyl-7-deaza-2-dATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase I, thermostable | polymer | 540 | 60937.0 | 1 | UniProt (P19821) Pfam (PF09281) Pfam (PF00476) | Thermus aquaticus | Taq polymerase 1 |
| 2 | B (B) | DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3') | polymer | 12 | 3617.4 | 1 | |||
| 3 | C (C) | DNA (5'-D(*AP*AP*AP*TP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3') | polymer | 16 | 4939.2 | 1 | |||
| 4 | D (A) | 5-(5-aminopent-1-yn-1-yl)-7-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 571.3 | 1 | Chemie (0L4) | |||
| 5 | E, F, N (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | G, J, L, O (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | H, K, P, Q (A, C) | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 8 | I, M (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | R, S, T (A, B, C) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69493.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1147.5 | |
| All* | Total formula weight | 70641.0 |
