3OJU

Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing c5 modified thymidies

Summary for 3OJU

Related3OJS 3LWL 3LWM 3M8R 3M8S
DescriptorDNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
Functional Keywordsdna polymerase, c5 modified nucleotide analogs, binding pocket, spin-labeled triphosphate, transferase-dna complex, transferase/dna
Biological sourceThermus aquaticus
Total number of polymer chains3
Total molecular weight72386.99
Authors
Marx, A.,Diederichs, K.,Obeid, S. (deposition date: 2010-08-23, release date: 2010-12-15, Last modification date: 2017-11-08)
Primary citation
Obeid, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A.
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.
Proc.Natl.Acad.Sci.USA, 107:21327-21331, 2010
PubMed: 21123743 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1013804107
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers140.6%3.6%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report