4DER
Crystal Structure of the Wild Type TTR Binding Apigenin (TTRwt:API)
Summary for 4DER
Entry DOI | 10.2210/pdb4der/pdb |
Related | 3KGS 3KGT 3KGU 3NEE 3NEO 3NES 4DES 4DET 4DEU 4DEW |
Descriptor | Transthyretin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta sandwich, amyloidosis, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 26039.00 |
Authors | Trivella, D.B.B.,Polikarpov, I. (deposition date: 2012-01-21, release date: 2012-11-21, Last modification date: 2023-09-13) |
Primary citation | Trivella, D.B.,Dos Reis, C.V.,Lima, L.M.,Foguel, D.,Polikarpov, I. Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis. J.Struct.Biol., 180:143-153, 2012 Cited by PubMed: 22842046DOI: 10.1016/j.jsb.2012.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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