4DEW
Crystal Structure of the Wild Type TTR Binding Luteolin (TTRwt:LUT)
Summary for 4DEW
| Entry DOI | 10.2210/pdb4dew/pdb |
| Related | 3KGU 4DER 4DES 4DET 4DEU |
| Descriptor | Transthyretin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (3 entities in total) |
| Functional Keywords | beta sandwich, amyloidosis, transport protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P02766 |
| Total number of polymer chains | 2 |
| Total formula weight | 32382.44 |
| Authors | Trivella, D.B.B.,Polikarpov, I. (deposition date: 2012-01-22, release date: 2012-11-21, Last modification date: 2023-09-13) |
| Primary citation | Trivella, D.B.,Dos Reis, C.V.,Lima, L.M.,Foguel, D.,Polikarpov, I. Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis. J.Struct.Biol., 180:143-153, 2012 Cited by PubMed: 22842046DOI: 10.1016/j.jsb.2012.07.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.899 Å) |
Structure validation
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