3KGS
V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5
Summary for 3KGS
Entry DOI | 10.2210/pdb3kgs/pdb |
Related | 3KGT 3KGU |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | transport protein, ttr, transthyretin, amyloid, amyloidosis, hormone, neuropathy, polymorphism, secreted, thyroid hormone, transport |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27618.85 |
Authors | Trivella, D.B.,Polikarpov, I. (deposition date: 2009-10-29, release date: 2010-03-23, Last modification date: 2023-09-06) |
Primary citation | Trivella, D.B.,Bleicher, L.,Palmieri, L.C.,Wiggers, H.J.,Montanari, C.A.,Kelly, J.W.,Lima, L.M.,Foguel, D.,Polikarpov, I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J.Struct.Biol., 170:522-531, 2010 Cited by PubMed: 20211733DOI: 10.1016/j.jsb.2010.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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