4AZI

Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

Summary for 4AZI

• Entry DOI: 10.2210/pdb4azi/pdb
• Related: 2YL5 2YL6 2YL8 2YL9 2YLA 2YLL 4AZ5 4AZ6 4AZ7 4AZB 4AZC 4AZG 4AZH
• Descriptor: BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: hydrolase
• Biological source: STREPTOCOCCUS PNEUMONIAE
• Cellular location: Secreted, cell wall; Peptidoglycan-anchor (Potential): P49610
• Total number of polymer chains: 2
• Total formula weight: 101626.23

Authors

Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2012-06-26, release date: 2013-07-10, Last modification date: 2023-12-20)

• Primary citation: Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B.; Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.; Org.Biomol.Chem., 11:7907-, 2013; PubMed: 24132305; DOI: 10.1039/C3OB41579A

Experimental method

X-RAY DIFFRACTION (1.98 Å)