2YL8

Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis

Summary for 2YL8

Entry DOI	10.2210/pdb2yl8/pdb
Related	2YL5 2YL6 2YL9 2YLA 2YLL
Descriptor	BETA-N-ACETYLHEXOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	hydrolase
Biological source	STREPTOCOCCUS PNEUMONIAE
Cellular location	Secreted, cell wall; Peptidoglycan-anchor (Potential): P49610
Total number of polymer chains	1
Total formula weight	52206.28
Authors	Pluvinage, B.,Higgins, M.A.,Abbott, D.W.,Robb, C.,Dalia, A.B.,Deng, L.,Weiser, J.N.,Parsons, T.B.,Fairbanks, A.J.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2011-05-31, release date: 2011-09-07, Last modification date: 2020-07-29)
Primary citation	Pluvinage, B.,Higgins, M.A.,Abbott, D.W.,Robb, C.,Dalia, A.B.,Deng, L.,Weiser, J.N.,Parsons, T.B.,Fairbanks, A.J.,Vocadlo, D.J.,Boraston, A.B. Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis. Structure, 19:1603-, 2011 Cited by PubMed: 22078560 DOI: 10.1016/J.STR.2011.08.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation