4AZ5

Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH

Summary for 4AZ5

Entry DOI	10.2210/pdb4az5/pdb
Related	2YL5 2YL6 2YL8 2YL9 2YLA 2YLL 4AZ6 4AZ7
Descriptor	BETA-N-ACETYLHEXOSAMINIDASE, (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	hydrolase
Biological source	STREPTOCOCCUS PNEUMONIAE
Cellular location	Secreted, cell wall ; Peptidoglycan-anchor : P49610
Total number of polymer chains	1
Total formula weight	49066.88
Authors	Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2012-06-22, release date: 2013-07-10, Last modification date: 2023-12-20)
Primary citation	Pluvinage, B.,Stubbs, K.A.,Vocadlo, D.J.,Boraston, A.B. Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11:7907-, 2013 Cited by PubMed: 24132305 DOI: 10.1039/C3OB41579A PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.73 Å)

Structure validation