4AUO

Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide

Summary for 4AUO

Entry DOI	10.2210/pdb4auo/pdb
Related	1AYK 1CGE 1CGF 1CGL 1HFC 1SU3 2AYK 2CLT 2J0T 2TCL 3AYK 4AYK 966C
Descriptor	INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase-peptide complex, hydrolase/peptide
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P03956
Total number of polymer chains	8
Total formula weight	107741.06
Authors	Manka, S.W.,Carafoli, F.,Visse, R.,Bihan, D.,Raynal, N.,Farndale, R.W.,Murphy, G.,Enghild, J.J.,Hohenester, E.,Nagase, H. (deposition date: 2012-05-18, release date: 2012-07-11, Last modification date: 2023-12-20)
Primary citation	Manka, S.W.,Carafoli, F.,Visse, R.,Bihan, D.,Raynal, N.,Farndale, R.W.,Murphy, G.,Enghild, J.J.,Hohenester, E.,Nagase, H. Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1 Proc.Natl.Acad.Sci.USA, 109:12461-, 2012 Cited by PubMed: 22761315 DOI: 10.1073/PNAS.1204991109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation