4AYK

CATALYTIC FRAGMENT OF HUMAN FIBROBLAST COLLAGENASE COMPLEXED WITH CGS-27023A, NMR, 30 STRUCTURES

Summary for 4AYK

Entry DOI	10.2210/pdb4ayk/pdb
Descriptor	PROTEIN (COLLAGENASE), ZINC ION, CALCIUM ION, ... (4 entities in total)
Functional Keywords	matrix metalloproteinase, hydrolase, metalloprotease, glycoprotein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	19429.89
Authors	Powers, R.,Moy, F.J. (deposition date: 1999-02-01, release date: 1999-06-05, Last modification date: 2023-12-27)
Primary citation	Moy, F.J.,Chanda, P.K.,Chen, J.M.,Cosmi, S.,Edris, W.,Skotnicki, J.S.,Wilhelm, J.,Powers, R. NMR solution structure of the catalytic fragment of human fibroblast collagenase complexed with a sulfonamide derivative of a hydroxamic acid compound. Biochemistry, 38:7085-7096, 1999 Cited by PubMed: 10353819 DOI: 10.1021/bi982576v PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation