4A4C
Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
Summary for 4A4C
Entry DOI | 10.2210/pdb4a4c/pdb |
Related | 1B47 1FBV 1M61 1U59 1UR6 1W4U 1YVH 2C4O 2CBL 2CLW 2ESK 2ESO 2ESP 2ESQ 2Y1M 2Y1N 4A49 4A4B |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, UBIQUITIN-CONJUGATING ENZYME E2 D2, ... (6 entities in total) |
Functional Keywords | ligase-transferase complex, ligase/transferase |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 63423.20 |
Authors | Dou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T. (deposition date: 2011-10-08, release date: 2012-01-25, Last modification date: 2023-12-20) |
Primary citation | Dou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T. Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl Nat.Struct.Mol.Biol., 19:184-, 2012 Cited by PubMed: 22266821DOI: 10.1038/NSMB.2231 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.704 Å) |
Structure validation
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