2Y1M
Structure of native c-Cbl
Summary for 2Y1M
| Entry DOI | 10.2210/pdb2y1m/pdb |
| Related | 1B47 1FBV 1YVH 2CBL 2Y1N 4A49 4A4B 4A4C |
| Descriptor | E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | ligase, ubiquitin ring e3 ligase |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm: P22681 |
| Total number of polymer chains | 6 |
| Total formula weight | 270597.55 |
| Authors | Dou, H.,Sibbet, G.J.,Huang, D.T. (deposition date: 2010-12-08, release date: 2012-01-18, Last modification date: 2023-12-20) |
| Primary citation | Dou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T. Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19:184-, 2012 Cited by PubMed: 22266821DOI: 10.1038/NSMB.2231 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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