1YVH
Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide
Summary for 1YVH
Entry DOI | 10.2210/pdb1yvh/pdb |
Descriptor | CBL E3 ubiquitin protein ligase, 13-mer fragment of SH2 and PH domain-containing adapter protein APS, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | x-ray crystallography; phosphotyrosine; adapter protein, ligase, signaling protein, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P22681 Q9Z200 |
Total number of polymer chains | 2 |
Total formula weight | 39859.06 |
Authors | Hu, J.,Hubbard, S.R. (deposition date: 2005-02-15, release date: 2005-03-08, Last modification date: 2023-11-15) |
Primary citation | Hu, J.,Hubbard, S.R. Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins J.Biol.Chem., 280:18943-18949, 2005 Cited by PubMed: 15737992DOI: 10.1074/jbc.M414157200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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