2CBL

N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70

Summary for 2CBL

Entry DOI	10.2210/pdb2cbl/pdb
Descriptor	PROTO-ONCOGENE CBL, ZAP-70, CALCIUM ION, ... (4 entities in total)
Functional Keywords	proto-oncogene, signal transduction, phosphotyrosine binding, sh2, complex (proto-oncogene-peptide), complex (proto-oncogene-peptide) complex, complex (proto-oncogene/peptide)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P22681
Total number of polymer chains	2
Total formula weight	36814.31
Authors	Meng, W.,Sawasdikosol, S.,Burakoff, S.J.,Eck, M.J. (deposition date: 1998-08-28, release date: 1999-05-18, Last modification date: 2024-04-03)
Primary citation	Meng, W.,Sawasdikosol, S.,Burakoff, S.J.,Eck, M.J. Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398:84-90, 1999 Cited by PubMed: 10078535 DOI: 10.1038/18050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation