1FBV
STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES
Summary for 1FBV
Entry DOI | 10.2210/pdb1fbv/pdb |
Descriptor | SIGNAL TRANSDUCTION PROTEIN CBL, ZAP-70 PEPTIDE, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... (5 entities in total) |
Functional Keywords | cbl, ubch7, zap-70, e2, ubiquitin, e3, phosphorylation, tyrosine kinase, ubiquitination, protein degradation, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P22681 Nucleus : P68036 |
Total number of polymer chains | 3 |
Total formula weight | 64330.24 |
Authors | Zheng, N.,Wang, P.,Jeffrey, P.D.,Pavletich, N.P. (deposition date: 2000-07-17, release date: 2000-08-30, Last modification date: 2017-10-04) |
Primary citation | Zheng, N.,Wang, P.,Jeffrey, P.D.,Pavletich, N.P. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell(Cambridge,Mass.), 102:533-539, 2000 Cited by PubMed: 10966114DOI: 10.1016/S0092-8674(00)00057-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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