4HKK
Complex structure of human tankyrase 2 with apigenin
Summary for 4HKK
Entry DOI | 10.2210/pdb4hkk/pdb |
Related | 3U9H 3U9Y 3UA9 4HKI 4HKN 4HL5 4HLF 4HLG 4HLH 4HLK 4HLM 4HMH |
Descriptor | Tankyrase-2, ZINC ION, SULFATE ION, ... (7 entities in total) |
Functional Keywords | protein-ligand complex, diphtheria toxin like fold, transferase, adp-ribosylation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 55903.31 |
Authors | Narwal, M.,Haikarainen, T.,Lehtio, L. (deposition date: 2012-10-15, release date: 2012-10-31, Last modification date: 2023-09-20) |
Primary citation | Narwal, M.,Haikarainen, T.,Fallarero, A.,Vuorela, P.M.,Lehtio, L. Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56:3507-3517, 2013 Cited by PubMed: 23574272DOI: 10.1021/jm3018783 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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