3UA9

Crystal structure of human tankyrase 2 in complex with a selective inhibitor

Summary for 3UA9

Entry DOI	10.2210/pdb3ua9/pdb
Related	3U9H 3U9Y
Descriptor	Tankyrase-2, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywords	protein-ligand complex, diphtheria toxin like fold, adp-ribosylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9H2K2
Total number of polymer chains	2
Total formula weight	56145.71
Authors	Narwal, M.,Lehtio, L. (deposition date: 2011-10-21, release date: 2012-01-25, Last modification date: 2023-09-13)
Primary citation	Narwal, M.,Venkannagari, H.,Lehtio, L. Structural basis of selective inhibition of human tankyrases. J.Med.Chem., 55:1360-1367, 2012 Cited by PubMed: 22233320 DOI: 10.1021/jm201510p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation