4HLH
Crystal structure of Tankyrase 2 in complex with 4'-fluoroflavone
Summary for 4HLH
| Entry DOI | 10.2210/pdb4hlh/pdb |
| Related | 3U9H 3U9Y 3UA9 4HKI 4HKK 4HKN 4HL5 4HLF 4HLG 4HLK 4HLM 4HMH |
| Descriptor | Tankyrase-2, ZINC ION, SULFATE ION, ... (8 entities in total) |
| Functional Keywords | protein-ligand complex, diphtheria toxin like fold transferase, adp-ribosylation, transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 55829.26 |
| Authors | Narwal, M.,Haikarainen, T.,Lehtio, L. (deposition date: 2012-10-17, release date: 2012-10-31, Last modification date: 2024-02-28) |
| Primary citation | Narwal, M.,Haikarainen, T.,Fallarero, A.,Vuorela, P.M.,Lehtio, L. Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56:3507-3517, 2013 Cited by PubMed: 23574272DOI: 10.1021/jm3018783 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report
