4AUO
Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide
Summary for 4AUO
Entry DOI | 10.2210/pdb4auo/pdb |
Related | 1AYK 1CGE 1CGF 1CGL 1HFC 1SU3 2AYK 2CLT 2J0T 2TCL 3AYK 4AYK 966C |
Descriptor | INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase-peptide complex, hydrolase/peptide |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P03956 |
Total number of polymer chains | 8 |
Total formula weight | 107741.06 |
Authors | Manka, S.W.,Carafoli, F.,Visse, R.,Bihan, D.,Raynal, N.,Farndale, R.W.,Murphy, G.,Enghild, J.J.,Hohenester, E.,Nagase, H. (deposition date: 2012-05-18, release date: 2012-07-11, Last modification date: 2023-12-20) |
Primary citation | Manka, S.W.,Carafoli, F.,Visse, R.,Bihan, D.,Raynal, N.,Farndale, R.W.,Murphy, G.,Enghild, J.J.,Hohenester, E.,Nagase, H. Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1 Proc.Natl.Acad.Sci.USA, 109:12461-, 2012 Cited by PubMed: 22761315DOI: 10.1073/PNAS.1204991109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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