4ACP
Deactivation of human IgG1 Fc by endoglycosidase treatment
Summary for 4ACP
Entry DOI | 10.2210/pdb4acp/pdb |
Related | 1AJ7 1AQK 1BEY 1D5B 1D5I 1D6V 1DN2 1E4K 1FC1 1FC2 1FCC 1H3T 1H3U 1H3V 1H3W 1H3Y 1I7Z 1L6X 1OQX 1T83 1T89 2IWG 2J6E 2RCS 2WAH |
Descriptor | IG GAMMA-1 CHAIN C REGION, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | immune system, igg, antibody, kifunensine |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P01857 |
Total number of polymer chains | 2 |
Total formula weight | 54252.26 |
Authors | Raman, K.,Bowden, T.A.,Krishna, B.A.,Dwek, R.A.,Crispin, M.,Scanlan, C.N. (deposition date: 2011-12-16, release date: 2012-04-25, Last modification date: 2023-12-20) |
Primary citation | Baruah, K.,Bowden, T.A.,Krishna, B.A.,A Dwek, R.,Crispin, M.,Scanlan, C.N. Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions. J.Mol.Biol., 420:1-, 2012 Cited by PubMed: 22484364DOI: 10.1016/J.JMB.2012.04.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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