3ZZ4

Crystal structure of 3C protease mutant (T68A and N126Y) of coxsackievirus B3

Summary for 3ZZ4

• Entry DOI: 10.2210/pdb3zz4/pdb
• Related: 3ZYD 3ZYE 3ZZ3 3ZZ5 3ZZ6 3ZZ7 3ZZ8 3ZZ9 3ZZA 3ZZB 3ZZC 3ZZD
• Descriptor: 3C PROTEINASE (2 entities in total)
• Functional Keywords: hydrolase, picornaviridae
• Biological source: HUMAN COXSACKIEVIRUS
• Total number of polymer chains: 2
• Total formula weight: 40897.07

Authors

Tan, J.,Anand, K.,Mesters, J.R.,Hilgenfeld, R. (deposition date: 2011-08-31, release date: 2012-09-19, Last modification date: 2019-05-08)

• Primary citation: Tan, J.,Anand, K.,Mesters, J.R.,Hilgenfeld, R.; Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)