3QRF
Structure of a domain-swapped FOXP3 dimer
Summary for 3QRF
Entry DOI | 10.2210/pdb3qrf/pdb |
Related | 1a02 1owr 2a07 2as5 |
Descriptor | Nuclear factor of activated T-cells, cytoplasmic 2, Forkhead box protein P3, human hARRE2 DNA (Plus Strand), ... (6 entities in total) |
Functional Keywords | beta barrel, domain swap, forkhead domain, immnoglobulin fold, protein-dna complex, double helix, transcription regulation, dna binding, nucleus, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q13469 Nucleus : Q9BZS1 |
Total number of polymer chains | 10 |
Total formula weight | 130608.36 |
Authors | Bandukwala, H.S.,Wu, Y.,Feurer, M.,Chen, Y.,Barbosa, B.,Ghosh, S.,Stroud, J.C.,Benoist, C.,Mathis, D.,Rao, A.,Chen, L. (deposition date: 2011-02-17, release date: 2011-04-20, Last modification date: 2023-09-13) |
Primary citation | Bandukwala, H.S.,Wu, Y.,Feuerer, M.,Chen, Y.,Barboza, B.,Ghosh, S.,Stroud, J.C.,Benoist, C.,Mathis, D.,Rao, A.,Chen, L. Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells. Immunity, 34:479-491, 2011 Cited by PubMed: 21458306DOI: 10.1016/j.immuni.2011.02.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report