3QE9
Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with DNA (complex I)
Summary for 3QE9
Entry DOI | 10.2210/pdb3qe9/pdb |
Related | 3QEA 3QEB |
Descriptor | Exonuclease 1, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... (6 entities in total) |
Functional Keywords | exonuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UQ84 |
Total number of polymer chains | 6 |
Total formula weight | 93183.35 |
Authors | Orans, J.,McSweeney, E.A.,Iyer, R.R.,Hast, M.A.,Hellinga, H.W.,Modrich, P.,Beese, L.S. (deposition date: 2011-01-20, release date: 2011-04-20, Last modification date: 2024-02-21) |
Primary citation | Orans, J.,McSweeney, E.A.,Iyer, R.R.,Hast, M.A.,Hellinga, H.W.,Modrich, P.,Beese, L.S. Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Cell(Cambridge,Mass.), 145:212-223, 2011 Cited by PubMed: 21496642DOI: 10.1016/j.cell.2011.03.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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