3QE9
Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with DNA (complex I)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (Y, Z) | Exonuclease 1 | polymer | 352 | 39515.9 | 2 | UniProt (Q9UQ84) Pfam (PF00752) Pfam (PF00867) | Homo sapiens (human) | hExo1, Exonuclease I, hExoI |
| 2 | B, E (C, A) | DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3') | polymer | 13 | 3951.6 | 2 | |||
| 3 | C, F (D, B) | DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3') | polymer | 10 | 3045.0 | 2 | |||
| 4 | G, I (Y, Z) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | H, J (Y, Z) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | K, L, M, N, O... (Y, C, D, Z, A...) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
Y, Z: 1 - 352 (UniProt: Q9UQ84)
| PDB | External Database | Details |
|---|---|---|
| Ala 173 | Asp 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 93025.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 158.4 | |
| All* | Total formula weight | 93183.3 |
