3PXE

Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: E1836K

Summary for 3PXE

• Entry DOI: 10.2210/pdb3pxe/pdb
• Related: 1N5O 1T15 1T2U 1T2V 2ING 3PXA 3PXB 3PXC 3PXD
• Descriptor: Breast cancer type 1 susceptibility protein, phospho peptide (3 entities in total)
• Functional Keywords: brca1 protein, missense, protein binding, phosphopeptide recognition, brct domain, phospho-peptide binding, nuclear protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus . Isoform 3: Cytoplasm. Isoform 5: Cytoplasm : P38398
• Total number of polymer chains: 8
• Total formula weight: 102950.00

Authors

Coquelle, N.,Green, R.,Glover, J.N.M. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-09-13)

• Primary citation: Coquelle, N.,Green, R.,Glover, J.N.; Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.; Biochemistry, 50:4579-4589, 2011; PubMed: 21473589; DOI: 10.1021/bi2003795

Experimental method

X-RAY DIFFRACTION (2.85 Å)