3P10
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol
Summary for 3P10
Entry DOI | 10.2210/pdb3p10/pdb |
Related | 3f0d 3ieq 3ike 3ikf 3jvh 3k14 3ke1 3mbm 3P0Z |
Descriptor | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CHLORIDE ION, ZINC ION, ... (7 entities in total) |
Functional Keywords | seattle structural genomics center for infectious disease, ssgcid, ispf, cytidine, fol694, f69, mep pathway, isoprene biosynthesis, lyase, metal-binding |
Biological source | Burkholderia pseudomallei |
Total number of polymer chains | 3 |
Total formula weight | 59652.02 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2010-09-29, release date: 2010-11-10, Last modification date: 2024-02-21) |
Primary citation | Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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