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3O4S

Crystal Structure of HePTP with a Closed WPD Loop and an Ordered E-Loop

Summary for 3O4S
Entry DOI10.2210/pdb3o4s/pdb
Related1ZC0 2GP0 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4T 3O4U
DescriptorTyrosine-protein phosphatase non-receptor type 7, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsheptp, human hematopoietic tyrosine phosphatase catalytic domain mutant, lc-ptp, ptpn7, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P35236
Total number of polymer chains1
Total formula weight36269.65
Authors
Critton, D.A.,Page, R. (deposition date: 2010-07-27, release date: 2010-11-24, Last modification date: 2023-09-06)
Primary citationCritton, D.A.,Tautz, L.,Page, R.
Visualizing active-site dynamics in single crystals of HePTP: opening of the WPD loop involves coordinated movement of the E loop.
J.Mol.Biol., 405:619-629, 2011
Cited by
PubMed: 21094165
DOI: 10.1016/j.jmb.2010.11.020
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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