3O4S

Crystal Structure of HePTP with a Closed WPD Loop and an Ordered E-Loop

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein phosphatase non-receptor type 7	polymer	308	35232.8	1	UniProt (P35236) Pfam (PF00102) In PDB	Homo sapiens (human)	Protein-tyrosine phosphatase LC-PTP, Hematopoietic protein-tyrosine phosphatase, HEPTP
2	A	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	A	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
4		water	water		18.0	277	Chemie (HOH)

Sequence modifications

A: 44 - 339 (UniProt: P35236)

PDB	External Database	Details
Met -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Asp 72	Ser 93	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35232.8
Non-Polymers*	Number of molecules	11
	Total formula weight	1036.8
All*	Total formula weight	36269.6

*Water molecules are not included.