3D44
Crystal structure of HePTP in complex with a dually phosphorylated Erk2 peptide mimetic
Summary for 3D44
Entry DOI | 10.2210/pdb3d44/pdb |
Related | 1zc0 2gp0 2hvl 2qdc 2qdm 2qdp 3d42 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 7, Mitogen-activated protein kinase 1 peptide, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | heptp, human hematopoietic tyrosine phosphatase catalytic domain mutant, lc-ptp, ptpn7, erk2, ptp-peptide complex, mapk-derived peptide, hydrolase, phosphoprotein, protein phosphatase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P35236 Nucleus: P28482 |
Total number of polymer chains | 2 |
Total formula weight | 36448.20 |
Authors | Critton, D.A.,Tortajada, A.,Page, R. (deposition date: 2008-05-13, release date: 2009-03-17, Last modification date: 2023-11-15) |
Primary citation | Critton, D.A.,Tortajada, A.,Stetson, G.,Peti, W.,Page, R. Structural basis of substrate recognition by hematopoietic tyrosine phosphatase. Biochemistry, 47:13336-13345, 2008 Cited by PubMed: 19053285DOI: 10.1021/bi801724n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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